![]() Insomnia and daytime sleepiness are extremely prevalent in PD. Regression models showed that fatigue, depression, urinary, cardiovascular, and thermoregulatory dysfunctions were significant determinants of SCOPA-NS score (variance: 23%) cognitive impairment, urinary, cardiovascular, and pupillomotor disorders influenced SCOPA-DS score (variance: 14%). ![]() ![]() SCOPA-S subscales showed higher scores with the presence of most other NMS such as psychiatric complications and autonomic dysfunctions (p < 0.05). Weak-to-moderate correlations were found between sleep disturbances and other NMS (range: 0.14-0.37). Most of the sample declared nocturnal or daytime sleep problems (87.4%). Mean age (54% male) was 65.9 ± 11.2 years old, with disease duration of 8.1 ± 6.0 years and median HY = 2 (range: 1-5). Spearman correlation coefficients, Mann-Whitney test and multiple linear regression analysis were applied. ![]() To describe the prevalence of insomnia and hypersomnia in PD and analyze their relationship with other NMS.Ĭross-sectional, multicenter study including 388 PD patients evaluated with Hoehn and Yahr, Clinical Impression of Severity Index for PD, Scales for Outcomes in Parkinson's Disease (SCOPA)-Sleep(S), SCOPA-Cognition, SCOPA-Psychiatric Complications, SCOPA-Autonomic, Hospital Anxiety and Depression Scale, and fatigue and pain visual analogue scales. The association between sleep disorders and other non-motor symptoms (NMS) in Parkinson's disease (PD) has been scarcely investigated. ![]()
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